PHARMACOGENETICS OF CLOPIDOGREL AND ITS SIGNIFICANCE FOR THE CLINIC

Zhaipanov, M.T. (2019) PHARMACOGENETICS OF CLOPIDOGREL AND ITS SIGNIFICANCE FOR THE CLINIC. Scientific-Practical Journal of Medicine, "Vestnik KazNMU" (1). ISSN 2524 - 0692

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Abstract

The purpose of a brief review for the pharmacogenetics of clopidogrel and its significance for the clinic. The results of some studies conducted on the basis of pharmacogenetic testing are presented. Bedside aggregatometry can be recommended for patients on dual antiplatelet therapy in order to reduce the risk of fatal complications – thrombosis and bleeding, identify cases of resistance and compliance problems, which will significantly improve the quality of medical care, allow to personalize the antiplatelet therapy, reduce the cost of treatment, the number and duration of hospitalizations. In the treatment of patients, the results of pharmacogenetic studies should be considered, taking into account the populations of different nationalities, for the doctors to be confident in the safety and efficacy of drugs.

Item Type:	Article
Uncontrolled Keywords:	clopidogrel, pharmacogenetics, CYP2C19, pharmacogenetic test. antiplatelet therapy, aggregatometry
Subjects:	R Medicine > RM Therapeutics. Pharmacology
Divisions:	Научно-практический журнал "Вестник КазНМУ" > Выпуск №4 2016 год
Depositing User:	Mr Askhat Zhakaev
Date Deposited:	20 Jun 2019 11:24
Last Modified:	20 Jun 2019 11:24
URI:	http://repository.kaznmu.kz/id/eprint/15482

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